COVID-19 liver damage may be more common than previously thought
Researchers at the Yale Liver Center analyzed liver tests from 1,827 patients with COVID-19.
(Web Desk) - Compared with hospitalized patients in China, a new study finds higher rates of abnormal liver tests among patients receiving treatment in hospitals in the United States. Higher levels of liver enzymes seem to be associated with an increased risk of admission to intensive care and death.
Researchers at the Yale Liver Center in New Haven, CT, analyzed liver tests from 1,827 patients with COVID-19. All were admitted to Yale-New Haven Health hospitals between March 14 and April 23, 2020.
These tests measure levels of enzymes that the liver releases into the bloodstream when it sustains damage.
An analysis of data from China suggests that around 15% of hospitalized COVID-19 patients had abnormal liver test results. However, 42–67% of the patients in the Yale study had abnormal tests upon admission to the hospital, depending on which of two enzymes the tests measured.
During hospitalization, these figures rose to 62% and 83%, respectively.
The results appear in the journal Hepatology.
The researchers are unsure why the livers of COVID-19 patients in the U.S. are more likely to have sustained damage, but underlying health differences between Chinese and U.S. populations may be responsible.
