(Reuters) - Premier League leaders Liverpool have drawn Czech side Sparta Praha in the last 16 of the Europa League, while Bundesliga frontrunners Bayer Leverkusen will play Azerbaijan's Qarabag.
Europa Conference League holders West Ham United will face German side Freiburg and last season's runners-up Roma play Roberto De Zerbi's Brighton & Hove Albion.
Spain's Villarreal, the 2020-21 champions, will face French Ligue 1 club Olympique de Marseille.
Italy's AC Milan have drawn Slavia Prague, Benfica will play Rangers and Portuguese side Sporting face Serie A's Atalanta in the other ties.
Sparta Prague v Liverpool
Olympique de Marseille v Villareal
AS Roma v Brighton & Hove Albion
Benfica v Rangers
Freiburg v West Ham United
Sporting v Atalanta
AC Milan v Slavia Prague
Qarabag v Bayer Leverkusen
The first legs will be played on March 7, except for Sporting v Atalanta who will play their first-leg match on March 5. The second legs will be played on March 14.